This volume is the proceedings of BIUST Teaching, Research, and Innovation Symposium 2023 (TRDAIS 2023) was held as part of the 10th-anniversary celebration of Botswana International University of Science and Technology on the18 - 19 September 2023. It contains full papers and abstracts of submissions presented in three tracks comprising of posters, oral presentations, and innovations. There are 99 abstracts submitted at an acceptance rate of 98%.