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Phytochemical investigation of the aerial parts of Kleinia longiflora

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dc.contributor.supervisor Ofitlhile, Tshepo Pheko
dc.contributor.author Sewawa, Keabetswe
dc.date.accessioned 2022-05-03T09:43:54Z
dc.date.available 2022-05-03T09:43:54Z
dc.date.issued 2021-01
dc.identifier.citation Sewawa, K. (2021) Phytochemical investigation of the aerial parts of Kleinia longiflora, Master's Thesis, Botswana International University of Science and Technology: Palapye. en_US
dc.identifier.uri http://repository.biust.ac.bw/handle/123456789/432
dc.description Thesis (Msc Chemical and Forensic Sciences) --Botswana International University of Science and Technology, 2021. en_US
dc.description.abstract Kleinia longiflora belongs to the family Asteraceae and genus Kleinia (synonym Senecio) which comprises of about 40 species. Preliminary phytochemical investigation done on this plant showed the presence of terpenoids, tannins, alkaloids and flavonoids. The phytochemical investigation on the non-volatile compounds from the plant led to the isolation of a triterpenoid lupeol 1 (0.403 g), a flavonoid named isorhamnetin-5-O-α-rhamnopyranosyl (1'''-6'')-β-glucopyranose 11 (0.658 g), a steroid stigmasterol 12 (0.248 g). Hexane extract and Kleinia longiflora essential oil analysis was done using GC-MS. 21 compounds were found to be present in the hexane extract and the main constituents were found to be β-eudesmol (80.6%), lupeol (53.1%), ambrosin (48.4%) and (-)-α-panasinsen (43.6%). 20 compounds were identified from Kleinia longiflora essential oil and the main constituents of the oil were hexanedioic acid, bis (2-ethylhexyl) ester (71.5 %) which is a diester, hexadecanoic acid, 2-hydroxy-1-(hydroxymethyl) ethyl ester (63.2%) which is a fatty acid glycerol ester, cis-carveol (61.0%) which is a monoterpenoid alcohol and octadecanoic acid, 2,3-dihydroxypropyl ester (50.7%) which is a fatty acid ester. en_US
dc.language.iso en en_US
dc.publisher Botswana International University of Science and Technology en_US
dc.subject Asteraceae en_US
dc.subject GC-MS en_US
dc.subject Kleinia longiflora en_US
dc.subject β-eudesmol en_US
dc.subject lupeol en_US
dc.subject Ambrosin en_US
dc.title Phytochemical investigation of the aerial parts of Kleinia longiflora en_US
dc.description.level msc en_US
dc.description.accessibility unrestricted en_US
dc.description.department cfs en_US


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